Shape-Shifted Red Blood Cells: A Novel Red Blood Cell Stage?

Porcine red blood cells express a polyagglutinable red blood cell phenotype.

The shortage of human blood and organs has led to increased interest in animal substitutes. In both transplantation and transfusion, the greatest roadblock to the use of animal tissues is the expression of xenoantigens. A major xenoantigen in pigs is linear B (Gal α 1-3Gal β 14GlcNAc-R), a cross-reactive, B-like antigen expressed on red blood cells (RBCs) and other tissues that is recognized by...

Dog Red Blood Cells

Red blood cells from mature dogs contain less Na and more K than would be the case if they were in Donnan equilibrium with plasma. They have no ouabain-sensitive Na pump, and their membranes are deficient in Na, K-ATPase. Experiments are reported in which dog red cells were first loaded with supranormal quantities of Na and water and then reinjected into the dog. Over the course of 26-40 h the ...

Red blood cell "aggregability".

It is well understood that the extent of red blood cell (RBC) aggregation is determined by both plasmatic and cellular factors [10]. It is also clear that alterations of plasmatic and cellular factors may be related to separate disease processes [1]. For example, plasma composition may change (e.g., fibrinogen concentration increase) due to an acute phase response, thereby altering RBC aggregat...

Red blood cell glycophorins.

Red Blood Cell Disorders

precursors and progenitors to increase production of fetal hemoglobin. J Clin Invest 75: 547-557, 1985 51. Rosa RM, Bierer BE, Thomas R, Jeffrey BS, Stoff JS, Kruskall M, Robinson S, Bunn HF, Epstein FH: A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis. New Eng J Med303: 1138-1143, 1980 52. Leary M, Abramson N: Induced hyponatremia for sickle-cell crisis. Ne...